Osteoporosis and heart disease represent a significant public health problem, with a substantial public health impact.

Recently published data on a special form of vitamin K2, called menaquinone-7 (MK7), demonstrated its unique effect and potential benefits on heart disease and bone metabolism. Vitamin K2 is emerging as a key factor in regulating calcium in the body.

Insufficient Vitamin K2 leads to decreased bone mineral density, a key factor in osteoporosis, and to an excess of calcium in the arterial wall, which increases the risk of heart disease.

Vitamk7® exclusively manufactured by Gnosis, is the active isomer of Vit K2 with the highest bioavailability and longest half-life in the blood. Clinical trials were performed by Gnosis on the effect of Vitamk7® on the gamma carboxylation of ostecalcin in vivo study, and on PGE-2 synthesis in bone forming osteoblasts in vitro study.

Vitamk7® is available in powder and in oil forms, suitable for different dosages and formulations. Obtained through a patented natural fermentation process, Vitamk7® is natural and solvent free, and consists entirely of all-trans vitamin K2.


Gnosis is leader in the high yield production and supply of naturally derived and solvent-free Vitamin K2
products, obtained through a patented granted biofermentation processes from Bacillus subtilis natto cultures
and commercialized under the brand names of Vitamk7®

The powder form is available in a variety of concentrations ranging from 1000 ppm to 2500 ppm on different carriers, natural biomass and maltodextrin.

The natural biomass consists only of the dried media used for the fermentation process, containing vitamin K2 as MK-7. It is obtained by the simple process of spray-drying carried out on the biomass coming from fermentation after washing steps.

Natural biomass can undergone to an extraction process without the use of any chemical solvent in order to extract Vitamin K2 as MK-7, as raw concentrated oil, which is blended with maltodextrin to obtain a white powder.

Maltodextrin is a polysaccharide produced from starch by partial hydrolysis and currently used as a food additive. It has been found to be a very appropriate support for menaquinone-7, furnishing neutral sweet taste, low sweetness and good solubility. Widely used for its reliable stability it is rapidly metabolized in the blood stream guaranteeing the fast release of menaquinone-7 in the gastrointestinal tract.

> Technical Information
Grade: Oral
Packing size: 5 Kg - 25 Kg, LDPE bags
Powder form: Different grade assay
Certifications: Kosher

Vitamk7® produced according to the cGMP in a pharmaceutical approved manufacturing operations. Consist entirely of the natural, all-trans Menaquinone-7 demonstrated by advanced analysis techniques. The trans chemical structure is responsible of the highest bioavailability and longest half-life in the blood and has been proved by several human clinical trials.

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