Saccharomyces boulardii is a non-pathogenic, non-colonizing yeast with probiotic properties used in many countries as both a preventive and therapeutic agent for diarrhoea and other gastrointestinal disorders and not related to the yeast group to which Candida belongs.
Supplementation may be useful for controlling diarrhoea associated with antibiotic use and the consumption of unusual foods while travelling.

Saccharomyces boulardii taken orally produces lactic acid and some B vitamins as it becomes established. During use, friendly probiotic bacteria are allowed to colonize in the GI tract making Saccharomyces boulardii particularly beneficial in balancing intestinal microbiology. It is then eliminated after supplementation is stopped.

S. boulardii is being used both in the pharmaceutical and in nutritional industries.


This microorganism has a bioregulatory effect on the intestinal flora helping to maintain a normal balance of friendly bacteria in the intestines modulating immunity by boosting intestinal secretion of IgA. The protective effect of Saccharomyces boulardii involves several types of activity in the epithelial tissue of the digestive tract, including inactivation of bacterial toxins, stimulation of intestinal immune response, and release of polyamines.

The clinical activity of S. boulardii has been documented in various types of diarrhoea and is especially relevant to antibiotic-associated diarrhoea and recurrent Clostridium difficile intestinal infections; its particular capacity to survive gastric acidity and to resist all commonly used antibiotics (except anti-fungals) makes it a useful remedy for diarrhoea brought on by antibiotics.
Research has found that S. boulardii may support gut function with many conditions, including inflammatory bowel disease, irritable bowel syndrome and traveler's diarrhoea.

> Technical Information
Grade: Oral
Particle size: Different distributions
Packing size: 5 Kg - 10 Kg - 25 Kg, LDPE bags
Assay: 2.0 x 1010 CFU / g
Certifications: Kosher
Regulatory status: DMF in CTD format

Furthermore recent data has opened the door for new therapeutic uses of this yeast as an 'immunobiotic', promoting body's immune response and health through activation of the mucosal immune apparatus.